If some dielectric is present in the space between the charges, the net force acting on each charge is altered becuse charges are induced in the molecules of the intervening medium the force decreases K times.
F= 1 q1q2 (in vacuum )
4

0 r
2
F’= 1 . q1q2 (in medium)
4

0k r
2
K is dielectric constant.
Hope this helps you.