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inactive enzyme precursors such as pepsinogen for pepsin are called. activase polyglycoid zymogens cholenzyme

inactive enzyme precursors such as pepsinogen for pepsin are called.
  1. activase
  2. polyglycoid
  3. zymogens
  4. cholenzyme

Grade:12th pass

2 Answers

askIITians Faculty 164 Points
6 years ago
Hello Student
Correct Answer is 3) Zymogens
Proenzyme or Zymogen is the inactive precursor of an enzyme. They become reactive or active enzymes only at a particular pH, in presence of substrate or special treatment.
Raheema Javed
156 Points
6 years ago
The correct answer is (3) Zymogens.
A zymogen (or proenzyme) is an inactive enzyme precursor. A zymogen requires a biochemical change (such as a hydrolysis reaction revealing the active site, or changing the configuration to reveal the active site) for it to become an active enzyme.
The pancreas secretes zymogens partly to prevent the enzymes from digesting proteins in the cells in which they are synthesised. Enzymes like pepsin are created in the form of pepsinogen, an inactive zymogen. Pepsinogen is activated when chief cells release it into HCl which partially activates it. Another partially activated pepsinogen completes the activation by removing the peptide turning the pepsinogen into pepsin. Accidental activation of zymogens can happen when the secretion duct in the pancreas is blocked by a gallstone resulting in acute pancreatitis.

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