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the formation of acetyl coenzyme from pyruvic acid is the result of its reduction dehydration dephosphorylation oxidative decarboxylation

the formation of acetyl coenzyme from pyruvic acid is the result of its
  1. reduction
  2. dehydration
  3. dephosphorylation
  4. oxidative decarboxylation

Grade:12

2 Answers

Gaurav
askIITians Faculty 164 Points
6 years ago
Hello Student
Correct Answer is 4. Oxidative Carboxylation.

Pyruvic acid is oxidatively decarboxylated to form acetyl Co-A and CO2by the pyruvate dehydrogenase complex(PDC). Itcontains multiple copies of three enzymes thats located in themitochondriaof eukaryotic cells and in the cytosol of prokaryotes.
And it is a intemediate step of aerobic respiration .
Raheema Javed
156 Points
6 years ago
The conversion of pyruvate into acetyl coenzyme A is an oxidative decarboxylation reaction.
This reaction is also known as Pyruvate decarboxylation. This reaction uses pyruvate to form acetyl-CoA, releasing NADH, a reducing equivalent, and carbon dioxide via decarboxylation. It takes place in the presence of oxygen. This reaction is catalysed by an enzyme complex called Pyruvate Dehydrogenase complex. This reaction is very common in most organisms as a link between glycolysis and the citric acid cycle.

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