0

Guest

Courses New

what is mechanism of aldol reaction?????

what is mechanism of aldol reaction?????

Grade:12

1 Answers

rake
askIITians Faculty 73 Points
10 years ago
* The first step in base catalyzed aldol reaction is the abstraction of an a-hydrogen from the enolizable carbonyl compound to give aresonancestabilized enolate anion. Usually this step is slow and rate determining.171-1852_al1.gifNote: Usually hydroxide ion is used as a base, since it is less basic than the enolate ion. This ensures the formation of only small amount of enolate ion and is a necessary condition for further reaction of this ion with unionized carbonyl compound. Otherwise, if strong bases like amide are used, all the reactant molecules are converted to enolate ions and no further addition is possible.

*The next step is the nucleophilic addition of enolate anion to the carbonyl group of second aldehyde or ketone molecule. The final product formed after protic workup is aß-hydroxy carbonylcompound (an aldol)

171-1761_al2.gif

Think You Can Provide A Better Answer ?

Other Related Questions on Organic Chemistry

View all Questions »

ASK QUESTION

Get your questions answered by the expert for free

Answer and earn gift vouchers

Win Gift vouchers upto Rs 500/-

View courses by askIITians

Design classes One-on-One in your own way with Top IITians/Medical Professionals

Click Here Know More

Complete Self Study Package designed by Industry Leading Experts

Click Here Know More

Live 1-1 coding classes to unleash the Creator in your Child

Click Here Know More

a Complete All-in-One Study package Fully Loaded inside a Tablet!

Click Here Know More