Flag Organic Chemistry> What are the limitations of Hoffman amono...
question mark

What are the limitations of Hoffman amonolysis of alkyl or aryl halides for preparations of alkyl or aryl amines?

Yogiraj , 9 Years ago
Grade 12th pass
anser 3 Answers
Suraj Prasad

Last Activity: 9 Years ago

Halo alkanes react with alcoholic NH3to form amine . But when halo alkane is in excess, the reaction doesnot stop rather continues till tertiary amine is formed. This continuous ammonolysis is called Hoffman’s ammonolysis.
Limitation :
1) It yields mixture of primary,secondary , tertiary and also a quaternary ammonium salt.

2) Aromatic amines could not be prepared since aryl halides are much less reactive towards nucleophilic substitution reactions.

SHAIK HAFEEZUL KAREEM

Last Activity: 9 Years ago

Halo alkanes react with alcoholic NH3to form amine . But when halo alkane is in excess, the reaction doesnot stop rather continues till tertiary amine is formed. This continuous ammonolysis is called Hoffman’s ammonolysis.Limitation :1) It yields mixture of primary,secondary , tertiary and also a quaternary ammonium salt.2) Aromatic amines could not be prepared since aryl halides are much less reactive towards nucleophilic substitution reactions.

Saksham

Last Activity: 2 Years ago

Halo alkanes react with alcoholic NH3to form amine . But when halo alkane is in excess, the reaction doesnot stop rather continues till tertiary amine is formed. This continuous ammonolysis is called Hoffman’s ammonolysis.Limitation :1) It yields mixture of primary,secondary , tertiary and also a quaternary ammonium salt.2) Aromatic amines could not be prepared since aryl halides are much less reactive towards nucleophilic substitution reactions.

star
LIVE ONLINE CLASSES

Prepraring for the competition made easy just by live online class.

tv

Full Live Access

material

Study Material

removal

Live Doubts Solving

assignment

Daily Class Assignments