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Analdol condensationis anorganic reactionin which anenolor anenolate ionreacts with acarbonylcompound to form a ß-hydroxyaldehyde or ß-hydroxyketone, followed by adehydrationto give a conjugatedenone.
Aldol condensations are important inorganic synthesis, providing a good way to formcarbon–carbon bonds. TheRobinson annulationreaction sequence features an aldol condensation; theWieland-Miescher ketoneproduct is an important starting material for many organic syntheses. Aldol condensations are also commonly discussed in university levelorganic chemistryclasses as a good bond-forming reaction that demonstrates importantreaction mechanisms.In its usual form, it involves thenucleophilicaddition of aketoneenolateto analdehydeto form a ß-hydroxy ketone, or "aldol" (aldehyde + alcohol), a structural unit found in many naturally occurring molecules and pharmaceuticals.
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