please explain oxirane cleavage with mechanism

please explain oxirane cleavage with mechanism


1 Answers

879 Points
12 years ago

Dear student,

Ethylene oxide readily reacts with various compounds, breaking a C–O bond and opening the cycle. Its typical reactions are with nucleophiles which proceed via the SN2 mechanism both in acidic (weak nucleophiles: water, alcohols) and alkaline media (strong nucleophiles: OH, RO, NH3, RNH2, RR'NH, etc.). The general reaction scheme is

Mechanism of reaction with ethylene oxide

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