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Role of alcohol in Hoffman ammonolysis and reagent and role of reagentvnucleophilics attack by carboxylate group on alkyl hallide

Role of alcohol in Hoffman ammonolysis and reagent and role of reagentvnucleophilics attack by carboxylate group on alkyl hallide

Grade:12

2 Answers

Ravleen Kaur
askIITians Faculty 1452 Points
5 years ago
Halo alkanes react with alcoholic NH3 to form amine .But when halo alkane is in excess, the reaction does not stop rather continues till tertiary amine is formed. This continuousammonolysisis calledHoffman's ammonolysis.


prince sunjot dutt
58 Points
5 years ago
In Hoffman ammonolysis reactions to form primary, secondary, tertiary amines and then Quaternary ammonium salt, an alcohol is used as solvent.

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