>> Study Material
>> IIT JEE Chemistry
>> Organic Chemistry
>> Carbohydrates Amino Acids and Peptides
>> Synthesis of Alpha Amino Acids
Synthesis of α - amino acids
Protein can be hydrolyzed by refluxing with dilute hydrochloric acid to give a mixture of α - amino acids. The resulting mixture can be separated by
(a) fractional crystallization.
(b) Fractional distillation of their ester followed by hydrolysis (Fischer’s method)
(c) Selective precipitation as salt with phosphotungstic and picric acid.
(d) Distribution of amino acid between n – butanol saturated with water (Dakin’s method).
(e) Column, paper and gas chromatography.
By amination of α- halo acid
By Strecker Synthesis
Note: Generally the aldehyde is treated with a mixture of ammonium chloride and potassium cyanide in aqueous solution
(D) All are correct
Physical properties of amino acid
(i) Amino acids are generally, crystalline substance having sweet taste.
(ii) They melt with decomposition at higher temperature (more than 200°C).
(iii) They are soluble in water but insoluble in organic solvents