Anjali parashar
Last Activity: 8 Years ago
One of the step of Gabriel`s synthesis involves nucleophilic substitution of alkyl halide in which halo group is replaced by phthalimide ion . Aryl halide do not undergo nucleophilic substitution under ordinary conditions because of resonance stabilisation and partial double bond character of aryl halogen bond. Therefore, they don`t react with potassium phthalimide to form N-phenyl phthalimide. Consequently , aniline and other aromatic amines cannot be prepared by Gabriel`s phthalimide synthesis