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When DNA is hydrolysed, there is a definite relation among the quantities of different bases obtained. But for hydrolysis of RNA, it is not so. What does this suggest about the structure of DNA and RNA?

When DNA is hydrolysed, there is a definite relation among the quantities of different bases obtained. But for hydrolysis of RNA, it is not so. What does this suggest about the structure of DNA and RNA?

Grade:Upto college level

1 Answers

Raheema Javed
156 Points
9 years ago
Chargaff's rules state that DNA from any cell of all organisms should have a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine.
it was shown that this rule applies to four of the five types of double stranded genomes; specifically it applies to the eukaryotic chromosomes, the bacterial chromosomes, the double stranded DNA viral genomes, and the archeal chromosomes. It does not apply to organellar genomes (mitochondria and plastids) smaller than ~20-30 kbp, nor does it apply to single stranded DNA (viral) genomes or any type of RNA genome.

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