Why is the Factor of Safety taken into consideration while aircraft manufacturing

lower than that taken for automobile manufacturing although logically speaking there

are far more variable conditions under which an aircraft may have to function?

aircraft and spacecraft use 1.2 to 3.0 depending on the application and materials. Ductile, metallic materials tend to use the lower value while brittle materials use the higher values. The field of aerospace engineering uses generally lower design factors because the costs associated with structural weight are high (i.e. an aircraft with an overall safety factor of 5 would probably be too heavy to get off the ground). This low design factor is why aerospace parts and materials are subject to very stringent quality control and strict preventative maintenance schedules to help ensure reliability. A usually applied Safety Factor is 1.5, but for pressurized fuselage it is 2.0, and for main landing gear structures it is often 1.25.
For loading that is cyclical, repetitive, or fluctuating, it is important to consider the possibility of metal fatigue when choosing factor of safety. A cyclic load well below a material's yield strength can cause failure if it is repeated through enough cycles.