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daljeet singh Grade: 12
        

please explain oxirane cleavage with mechanism

6 years ago

Answers : (1)

SAGAR SINGH - IIT DELHI
879 Points
										

Dear student,


Ethylene oxide readily reacts with various compounds, breaking a C–O bond and opening the cycle. Its typical reactions are with nucleophiles which proceed via the SN2 mechanism both in acidic (weak nucleophiles: water, alcohols) and alkaline media (strong nucleophiles: OH, RO, NH3, RNH2, RR'NH, etc.). The general reaction scheme is


Mechanism of reaction with ethylene oxide








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6 years ago
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