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What are focal adhesion plaques? Please explain about it.

What are focal adhesion plaques? Please explain about it.

Grade:12

1 Answers

Adarsh
733 Points
4 years ago
Focal adhesion plaques are regions of local attachment between cells and the extracellular matrix. They are typically situated at or near the ends of actin filament bundles (stress fibres), which are anchored through intermediary proteins to the cytoplasmic domains of integrins. In turn, these are attached at their external ends to collagen or other filamentous structures in the extracellular matrix. They are usually short-lived: their formation and subsequent disruption are part of the motile behaviour of migratory cells.
 
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