spironolactone acts at which part of the nephron

1. its a site of action depending upon it concentration
2. it is steel the matter of research
3. it act on collecting tubules
4. it act on PCT

Hello Student
Correct Answer is 3. it acts on collecting tubules.
Spironolactone acts predominantly as a competitive antagonist of the aldosterone receptor and belongs to a class of pharmateucal drugs known as patassium sparing diuretics.

Spironolactone acts on collecting tubules (3).

Spironolactone: blocks the aldosterone receptors in the cortical collecting duct. This causes a decrease in sodium and water reabsorption and decreases potassium secreting.It is used primarily as a diuretic and antihypertensive, but may also be employed for the purpose of reducing elevated or unwanted androgen activity in the body.