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Sir in ncert there is one line that when we go in heights the binding capacity of haemoglobin decreases what does it means sir?

Sir in ncert there is one line that when we go in heights the binding capacity of haemoglobin decreases what does it means sir?

Grade:12th pass

4 Answers

Radha Shukla
178 Points
5 years ago
When we go in height their is more demand of oxygen and oxygen has to be available easily so to cope up binding capacity decreases and so as oxygen becomes easily available
Hafiz shah s.r
25 Points
5 years ago
It's because when we climb over heights,the partial pressure of oxygen will be less as compared to that at sea level.so as we climb Po2 decreases and thus binding amount of haemoglobin with oxygen decreases...
In order to Inc the oxygen binding capacity of haemoglobin we need to Inc partial pressure of oxygen by wearing an oxygen mask.
Deepti
12 Points
5 years ago
as we go up the oxygen is not binded that strongly to haemoglobin so it can be supplied to the organs as soon as soon as possible. 
Akhil Nair
11 Points
5 years ago
 
At high altitudes, the oxygen becomes relatively rare. Lower Air pressure makes it difficult for O2 to enter our blood from lungs. body would be in great need to take in more O2 in such situations to prevent hypoxia (oxygen deprivation)
To compensate for the reduced amount of O2, our body produces more RBCs hence more haemoglobin to carry more O2. 
This is fine till here. Now remember that O2 has an 'affinity' or attraction to haemoglobin at different tissue levels due to partial pressure differences. It binds tightly to haemoglobin at lung alvepialveoli-capillary level and loses it's affinity to remain bound at other tissue levels. This is how oxygen reaches different cells.
If the oxygen molecules don't unbind from haemoglobin the tissues will starve and die. A particular enzyme In the haemoglobin helps in reducing the affinity of oxygen so that the
bound acclimatization O2 molecules are released into tissues. 
In short, RBCs no/haemoglobin amount goes up, new blood capillaries are formed, lungs become larger, and at the same time O2 affinity for haemoglobin decreases to create a fine balance.
This is a type of body acclimatization. 
Hope it's clear.
 

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