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Please give a short explanation about intermediate junction

Please give a short explanation about intermediate junction

Grade:12

1 Answers

Adarsh
733 Points
7 years ago
Intermediate junction is a continuous, belt-like zone of adhesion around the apical perimeters of endothelial, mesothelial and epithelial cells, parallel and just basal to the tight junction in epithelia. High concentrations of cadherins occur in this zone; their cytoplasmic ends are anchored through the proteins vinculin and α-actinin to a layer of actin microfilaments. These junctions help to reinforce the intercellular attachment of the tight junction and prevent its mechanical disruption

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