a individual has low blood potassium and hypertension show that has blood aldosterone is very high. he might be suffering from

1. addison’s disease
2. cretinism
3. gigantism
4. conn’s disease

Hello Student
Correct Answer is 4. Conn’s disease
Conn’s Disease is a disease of the adrenal glands involving excess production of aldosterone. It caused high blood pressure in Humans.

The correct answer is (4) Conn’s disease

Aldosterone has effects on most or all cells of the body but, clinically, the most important actions are on cells of the late distal tubule and medullary collecting duct. In the principal cells aldosterone increases activity of basolateral membrane sodium-potassium ATPase and apical epithelial sodium channels, ENaC, as well as potassium channels, ROMK. These actions increase sodium reabsorption and potassium secretion. Since more sodium is reabsorbed than potassium secreted, it also makes the lumen more electrically negative, causing chloride to follow sodium. Water then follows sodium and chloride by osmosis. In Conn syndrome, these actions cause increased extracellular sodium and fluid volume and reduced extracellular potassium. Aldosterone also acts on intercalated cells to stimulate an apical proton ATPase, acidifying urine and alkalizing extracellular fluid.