How to calculate velocity of pulse in a non uniform rope

Pulse wave velocity (PWV) is the velocity at which the arterial pulse propagates through the circulatory system. PWV is used clinically as a measure of arterial stiffness.^[1][2] It is easy to measure invasively and non-invasively in humans, is highly reproducible,^[3] has a strong correlation with cardiovascular events and all-cause mortality,^[4][5][6][7] and was recognized by the European Society of Hypertension as an indicator of target organ damage and a useful additional test in the investigation of hypertension.^[8] A high pulse wave velocity (PWV) has also been associated with poor lung function.^[9]