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Grade 12th passOrganic Chemistry

What type of α carbon will you use to promote SN2 reaction?

Profile image of JAIME CAYAN
5 Years agoGrade 12th pass
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1 Answer

Profile image of Pawan Prajapati
5 Years ago
Answer ::

For Sn2 reaction ::

Requires an unhindered path to the back of the α carbon.
α and β branching block the path and hinder SN2.
Requires a good nucleophile.
Polar, aprotic solvents increase nucleophilicity.
Bulky groups on the nucleophile decrease nucleophilicity.

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