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We see that hydride ion transfer takes place in cannizzaros reaction. Why does such a shift not take place in aldol condensation as it seems to be possible?

Pranjal K , 11 Years ago
Grade upto college level
anser 1 Answers
GAURAV SINGH

Last Activity: 11 Years ago

Because in aldol reaction , we have a acidic hydrogen in the aldehyde or ketone and we have a base a reagent, so there will be acid base reaction, which will be the fast reaction, and then the conjugate base of aldehyde or ketone will attack the other molecule of aldehyde or ketone to complete the reaction. Now we can see that during the whole reaction there is no possibility of hydrogen transfer in aldol condensation


Thanks & Regards
Gaurav Singh
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BS-MS (in Chemistry)
IISER Bhopal

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