Question icon
Grade 12th passOrganic Chemistry

give mechanism of alpha elimination reaction.
give mechanism of alpha elimination reaction

Profile image of mukul gupta
9 Years agoGrade 12th pass
Answers icon

2 Answers

Profile image of Vikas TU
9 Years ago
It is a 2 step reaction ionization and De-Protonation.
And the leaving group leaves the Reactant and at the other side the Nucleophile gets attached to the product following with an unsaturated bond.
Profile image of DILIP
9 Years ago
A strong base removes acidic protons followed by loss of leaving group i.e. first a group or atom without its electron pair is lost, usually proton and then a group with its electron pair is lost.
 
These reactions are favored by
 
Presence of electron withdrawing group on α carbon atom (i.e. acidity of α hydrogen is increased). It is supported by the fact that reaction of alkyl bromides or iodides with base gave very less α elimination product than that of corresponding alkyl chlorides.
 
Use of very strong base favors α elimination. PhNa , a very strong base gave α elimination product in following reaction up to 94% whereas NaNH 2 or NaOMe did not give much yields.
 
IF U ARE SATISFIED WITH ANSWER , PLEASE CLICK APPROVED