1. Overall transformation : Ar-H to Ar-R 2. Named after Friedel and Crafts who discovered the reaction in 1877. 3. Reagent : normally the alkyl halide (e.g. R-Br or R-Cl) with aluminum trichloride, AlCl3, a Lewis acid catalyst. 4. The AlCl3 enhances the electrophilicity of the alkyl halide by complexing with the halide. 5. Electrophilic species : the carbocation (i.e. R +) formed by the "removal" of the halide by the Lewis acid catalyst 6. The reactive electrophile, the carbocation is prone to rearrangement to a more stable carbocation which will then undergo the alkylation reaction. alkylation with rearrangement1,2-hydride shift during a Friedel-Crafts reaction 7. Friedel-Crafts reactions are limited to arenes as or more reactive than mono-halobenzenes 8. Other Lewis acids such as BF3, FeCl3 or ZnCl2 can also be used 9. Other sources of carbocations can also be used: a)-from loss of water from alcohols treated with acid such as H2SO4 b)-from the protonation of alkenes by acid such as H2SO4 10. Alkylation products can also be obtained by the reduction of Friedel-Crafts acylation products