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convert phenol to 4-methoxyacetophenone

convert phenol to 4-methoxyacetophenone

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1 Answers

ruchi yadav
askIITians Faculty 27 Points
8 years ago

phenol + CH3COOH ----(H2SO4---> Ph-OCOCH3 (ester) -----anh. AlCl3 ---> 4 methoxyacetophenone at low temperature...

the first step is esterification with acetic acid and ethanoyl chloride can also be used.... and second step is fries rearrangement.

Thank You
Ruchi
Askiitians Faculty

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