Amit Askiitiansexpert
Last Activity: 14 Years ago
Steric Effect:
The effect on a chemical or physical property (structure, rate, or equilibrium constant) upon introduction of substituents having different steric requirements. The effect is basically associated with the fact that atoms and larger parts of a molecule occupy a certain region of space. When atoms or groups are brought together, hindrance will be induced, resulting in changes in shape, energy, reactivity, etc. Steric effects arise from contributions ascribed to strain as the sum of
nonbonded repulsions, bond angle strain, and bond stretches or compressions.
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