Thank you for registering.

One of our academic counsellors will contact you within 1 working day.

Please check your email for login details.
MY CART (5)

Use Coupon: CART20 and get 20% off on all online Study Material

ITEM
DETAILS
MRP
DISCOUNT
FINAL PRICE
Total Price: Rs.

There are no items in this cart.
Continue Shopping

write the methods of preparation of amino acid.

write the methods of preparation of amino acid. 

Grade:

2 Answers

Aman Bansal
592 Points
9 years ago

Dear Nikulas,

Methods of preparation of amino acids:         

 
 

(i)            Elimination of α - haloacids.

 
 
      Cl – CH2COOH + 2NH3 ———> H2NCH2COOH + NH4Cl
                                                           Glycine
 
 

(ii)          Gabriel phthalimide synthesis:

 

α halogenated acid or ester combines with potassium phthalimide. Product on hydrolysis gives α - amino acid.

 

90_Phthalic acid.JPG           

 

(iii) Knoop synthesis:

 

α - keto acid on treatment with NH3 forms an imine which on catalytic reduction gives amino acid.

 

      479_Pyruric acid.JPG

 

(iv) Strecker synthesis:

 

Aldehydes react with HCN and ammonia or NH4CN and the product on hydrolysis yields α - aminoacids.

 

 

        H                               H                                     H                                 H
        |          HCN                |                   NH3              |             H2O.H+           |
R — C = O ———> R —— C —— OH ———> R —— C — NH2 ———> R —— C —— NH2
 
 
                                         |                                       |                                   |
     Aldehyde                    CN                                   CN                             COOH
                                 Cyanohydrin                       Aminonitrile                 α - amino acid

 

 

Some of the reactions given by amino acids are as follows:

 

               2357_Amino acid reaction.JPG

Best Of Luck...!!!!

Cracking IIT just got more exciting,It’s not just all about getting assistance from IITians, alongside Target Achievement and Rewards play an important role. ASKIITIANS has it all for you, wherein you get assistance only from IITians for your preparation and win by answering queries in the discussion forums. Reward points 5 + 15 for all those who upload their pic and download the ASKIITIANS Toolbar, just a simple  to download the toolbar….

So start the brain storming…. become a leader with Elite Expert League ASKIITIANS

Thanks

Aman Bansal

Askiitian Expert

Rishi Sharma
askIITians Faculty 646 Points
one year ago
Dear Student,
Please find below the solution to your problem.
Methods of preparation of amino acids:
(i)Elimination of α - haloacids.
645-703_027.PNG
(ii)Gabriel phthalimide synthesis:α-halogenatedacid or ester combines with potassium phthalimide. Product on hydrolysis givesα - amino acid.
645-1236_0027.PNG
(iii)Knoop synthesis:α -keto acid on treatment with NH3forms an imine which on catalytic reduction gives amino acid.
645-991_00027.PNG
Thanks and Regards

Think You Can Provide A Better Answer ?

Provide a better Answer & Earn Cool Goodies See our forum point policy

ASK QUESTION

Get your questions answered by the expert for free