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PLEASE EXPLAIN R AND S ISOMERS

SHIVAM JAIN , 14 Years ago
Grade 12
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Godfrey Classic Prince

Dear SHIVAM JAIN,

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Last Activity: 14 Years ago
SAGAR SINGH - IIT DELHI

Remembering the geometric implication of wedge and hetced bonds, an observer (the eye) notes whether a curved arrow drawn from the # 1 position to the # 2 location and then to the # 3 position turns in a clockwise or counter-clockwise manner. If the turn is clockwise, as in the example on the right, the configuration is classified R. If it is counter-clockwise, as in the left illustration, the configuration is S. Another way of remembering the viewing rule, is to think of the asymmetric carbon as a steering wheel. The bond to the lowest priority group (# 4) is the steering column, and the other bonds are spokes on the wheel. If the wheel is turned from group # 1 toward group # 2, which in turn moves toward group # 3, this would either negotiate a right turn (R) or a left turn (S). This model is illustrated below for a right-handed turn, and the corresponding (R)-configurations of lactic acid and carvone are shown to its right. The stereogenic carbon atom is colored magenta in each case, and the sequence priorities are shown as light blue numbers. Note that if any two substituent groups on a stereogenic carbon are exchanged or switched, the configuration changes to its mirror image.

 

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