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Grade 12th passOrganic Chemistry

1.The concentration of drug X in aqueous solution drops by 10% per month when stored at room temperature. If the degradation occurs by first order, what concentration will remain if a 5 mg/ml solution of the drug is stored under the same conditions for 3 months?
2. A 5 gm/100 ml solution of drug X is stored in a closed test tube at 25°C. If the rate of degradation of the drug is 0.05 day−1, calculate the time required for the initial concentration to drop to (a) 50% (half-life) and (b) 90% (shelf-life) of its initial value.
3. A 5 gm/100 ml solution of drug X is stored in a closed test tube at 25°C. If the rate of degradation of the drug is 0.05 day−1, calculate the time for the drug concentration to degrade to 2.5 mg/ml.

Profile image of OdakaMHarris
7 Years agoGrade 12th pass
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2 Answers

Profile image of Arun
7 Years ago
Dear student
 
Please ask only one question in one thread.
 
2.)
 
from the unit of the rate constant (day^-1), it is obvious that it is a forst order degradation process.
hence At = Ao e^-kt
 
now
t ½ = 0.693/k = 13.9 days
 
similarly t(90%) = 2.1 days
 
Profile image of Fhjjnngfff
5 Years ago
A 5 gm / 100 ml solution of drug X is stored in a closed test tube at 25 °C. If the rate of degradation of the drug is 0.05 day - 1, calculate the time required for the initial concentration to drop to (a) 50% (half - life) and (b) 90% (shelf-life) of its initial value