Thank you for registering.

One of our academic counsellors will contact you within 1 working day.

Please check your email for login details.
MY CART (5)

Use Coupon: CART20 and get 20% off on all online Study Material

ITEM
DETAILS
MRP
DISCOUNT
FINAL PRICE
Total Price: Rs.

There are no items in this cart.
Continue Shopping

Salicylic acid can be esterified to aspirin with (CH3CO)20 in the presence of CONC.H2So4.While with pyridine is added in reaction the reaction with CH3COCl.Why?

Salicylic acid can be esterified to aspirin with (CH3CO)20 in the presence of CONC.H2So4.While with pyridine is added in reaction the reaction with CH3COCl.Why?

Grade:12

1 Answers

ruchi yadav
askIITians Faculty 27 Points
7 years ago


The most common medical ester is aspirin (ASA; acetyl salicylic acid). Other drugs such as Worm Guard (anti-wormer), Maxicaine (local anesthetic), Malathion (organophosphate), Mebendazole (antihelmenthic), Demerol (narcotic analgesic) and Equinil (sedative) are also esters.
The starting reactants for this experiment are salicylic acid and acetic anhydride (structures are shown above).

Salicylic acid reacts better with acetic anhydride than acetic acid, so acetic acid will provide the acetyl group which will react with the alcoholic -OH group on the salicylic acid.


Thank You
Ruchi
Askiitians Faculty


Think You Can Provide A Better Answer ?

Provide a better Answer & Earn Cool Goodies See our forum point policy

ASK QUESTION

Get your questions answered by the expert for free