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Dear GURPREET SAINI,
Sadly,No !
BioTechnology is not an Optional Subject in UPSC Examination in both the Preliminary & Main Examinations !
But you can Take Botany (or) Zoology as an Optional Subject for Both Preliminary & Main Examinations !
Check out the link given below to know more
http://www.onestopias.com/subjects/
All the Best & Good Luck !!;
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