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Why does synthesis of DNA proceed only in the 5′ to 3′ direction?ADNA polymerases can only add nucleotides to the 3′ end of a polynucleotide strand.BThe 3′ end of the polynucleotide molecule is more electronegative than the 5′ end.CThis is the direction in which the two strands of DNA unzip.DThe chromosomes are always aligned in the 5′ to 3′ direction in the nucleus.

Shamit Jain , 4 Years ago
Grade 10
anser 1 Answers
ankit singh

Last Activity: 4 Years ago

 

  • DNA polymerase enzyme helps in the synthesis of DNA molecules from deoxyribonucleotides, the building blocks of DNA. They are essential for DNA replication and usually works in a pair to create identical DNA strands.
  • DNA polymerases require 3' OH group for the initiation of synthesis of DNA strand. Therefore, it can synthesize in only one direction by extending the 3' end of the pre-existing nucleotide chain. Hence, DNA polymerase moves along the template strand in 3' - 5' direction and the daughter strand is formed in a 5' - 3' direction.
So, the correct option is 'DNA polymerases can only add nucleotides to the 3′ end of a polynucleotide strand'. 

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