Rituraj Tiwari
Last Activity: 4 Years ago
Both pepsin and trypsin are proteolytic enzymes. Pepsin is secreted in the stomach, whereas trypsin is a component of pancreatic juice. Pepsinogen is activated to pepsin in the stomach on exposure to hydrochloric acid. The optimum pHfor activity of pepsin is 1.8.Pepsin is a strong endopeptidase andbreaks proteins into smallermolecules like peptones, proteosesand peptides.Trypsinogen is activated by the action of enterokinase into active trypsin.Enterokinase is secreted by the duodenal mucosa for activation of trypsinogen. Trypsin and chymotrypsin are endopeptidase type of enzymes and are active in alkaline pH i.e., 7.5 to 8. Theydissociate proteins into peptones and proteoses. Thus, the correct answer is option D.