Anjali Ahuja
Last Activity: 9 Years ago
Hello Student
Oxidation of of palmitic acid yields 7 NADH + 7 FADH2 + 8 acetyl-CoA in 7 cycles of mitochondrial beta oxidation.
1NADH produces3 ATP molecules and 1FADH2 produces 2ATP molecules. Every acetyl-CoA yields 3 NADH + 1 FADH2 + 1 GTP (=ATP) during Krebs cycle.
Now, 7 NADH + 7 FADH2 + 8 acetyl-CoA = 7*3 + 7*2 + 8 (3*3 + 1*2 + 1) = 131
Now we have 131 ATP molecules. However we have to used 2 ATP molecules for the initial activation of every fatty acid that is going to be oxidized in the mitochondria.
So it is 131-2 = 129 ATPs.
Hope everything is clear :)