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Distinguish between Exonucleases and Endonucleases.

john wick , 4 Years ago
Grade 12
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Vikas TU

Last Activity: 4 Years ago

Dear student 
Exonucleases are enzymes that cleave DNA sequences in a polynucleotide chain from either the 5' or 3' end one at a time. Endonucleases cleave the nucleotide sequence from the middle.

Vikas Amritiya

Last Activity: 4 Years ago

Exonucleases are nuclease which cut off nucleotides from 5 or 3 ends of DNA molecule. 
Endonucleases are nucleases which cleave DNA duplex at any point except the ends. Leading to blunt or sticky ends. 

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