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Assertion : Hutington’s disease is caused due to low level of Gamma amino butyric acid Reason : a child of an affected person typically has 50% chance of inheriting the disease because it have low level of GABA

Assertion : Hutington’s disease is caused due to low level of Gamma amino butyric acid
Reason : a child of an affected person typically has 50% chance of inheriting the disease because it have low level of GABA

Grade:12th pass

1 Answers

Simran Vinaik
askIITians Faculty 1230 Points
5 years ago
Hutington is caused due to genetic mutation which is autosomal and dominant. i.e. why a person withHuntington'sdisease has one non-HDalleleand one HDallele. Hence, there is a50% chance that the non-HDallelewill bepassedon and a50% chance that the HDallelewill bepassedon. This means that each child of an individual with HD has a50% chance of getting the HDallele.

In HD shows loss of neurotransmitters, including GABA, acetylcholine and glutamate, which correlates with the loss of small neurons.

So actual reason is genetic mutation and 50% chances are because it is autosomal dominant.

So both are incorrect

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