d ans is d 1st option

=¹⁰C­_r(x/2)^10-r(-3/x²)^r

=¹⁰C­_r(x/2)^10-r(-3)^r(x^-2)^r

10-r-2r=4

10-3r=4

r=2

Coefficient Of x⁴ in

=¹⁰C­₂(1/2)^10-2(-3)²

=45*9/2⁸

=405/256