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What is the difference between cellular and cytokine barriers?

What is the difference between cellular and cytokine barriers?

Grade:12th pass

1 Answers

Raheema Javed
156 Points
6 years ago
Cellular Barriers
Leukocytes (white blood cells) act like independent, single-celled organisms and are the second arm of the innate immune system.The innate leukocytes include thephagocytes(macrophages,neutrophils, anddendritic cells),mast cells,eosinophils,basophils, andnatural killer cells. These cells identify and eliminate pathogens, either by attacking larger pathogens through contact or by engulfing and then killing microorganisms.Innate cells are also important mediators in the activation of theadaptive immune system.

Cytokine barriers
If anyantigengets through the chemical andphysical barriers,innate immunityprovides a first line of defense. In this type of response cytokines play a very important role, both directly(for example, blocking viral replication by the interferons)and by means of different immune-modulatory mechanismsthat trigger the inflammatory response, produce and elevation on the body temperature, activate NK cells and macrophages, etc. Those cytokines that have a role in this step are mainly produced by monocytes-macrophages and other non-immunological cells, such as fibroblasts and endothelial cells.

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