D-glucose and L-glucose differ in:(A) Configuration at the highest number chiral carbon.(B) Configuration at first chiral carbon(C) Configuration at each chiral carbon(D) Configuration at the second chiral carbon.

D-glucose and L-glucose differ in (C) Configuration at each chiral carbon.

To elaborate, D- and L- designations in sugars refer to the configuration of the molecule at every chiral center relative to the reference molecule, glyceraldehyde. In the case of glucose, which has four chiral centers, the configurations of all these centers in D-glucose are the mirror image of those in L-glucose. Therefore, each chiral carbon in D-glucose has the opposite configuration in L-glucose. This enantiomeric relationship means that D-glucose and L-glucose are non-superimposable mirror images of each other, differing in the configuration at every chiral carbon.