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11 grade chemistry others

Which reaction sequence would be best to prepare 3-chloroaniline from benzene?

  • A. Chlorination, Nitration, Reduction
  • B. Nitration, Chlorination, Reduction
  • C. Nitration, Reduction, Chlorination
  • D. Nitration, Reduction, Acetylation, chlorination, hydrolysis

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11 Months agoGrade
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1 Answer

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ApprovedApproved Tutor Answer11 Months ago

To prepare 3-chloroaniline from benzene, the most effective reaction sequence is:

Nitration, Chlorination, Reduction

This sequence works as follows:

  • Nitration: First, introduce a nitro group to the benzene ring, forming nitrobenzene.
  • Chlorination: Next, chlorinate the nitrobenzene to add a chlorine atom at the meta position, resulting in 3-chloronitrobenzene.
  • Reduction: Finally, reduce the nitro group to an amine group, yielding 3-chloroaniline.

Thus, the correct answer is B. Nitration, Chlorination, Reduction.