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11 grade chemistry others

Name two reagents used for acylation of benzene.

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1 Year agoGrade
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1 Year ago

Two common reagents used for the acylation of benzene are:

Acetyl Chloride (CH3COCl): Acetyl chloride is a reactive acylating agent that reacts with benzene in the presence of a Lewis acid catalyst, such as aluminum chloride (AlCl3), to form an acetylbenzene (acetophenone) product.

Acetic Anhydride (CH3CO)2O: Acetic anhydride is another acylating agent that can be used to acylate benzene. It reacts with benzene in the presence of a Lewis acid catalyst to yield acetylbenzene as the product.

In both cases, the Lewis acid catalyst is used to generate an acylium ion (R-CO+) from the acylating agent, which then reacts with the benzene ring to form the acylated product. The mechanism involves electrophilic aromatic substitution.