The correct answer is:
D. Cell membrane structure
Archaebacteria (also known as Archaea) and Eubacteria (also known as Bacteria) are two distinct domains of microorganisms. One of the key differences between them is the structure of their cell membranes. Archaebacteria have unique cell membrane lipids that are different from those found in Eubacteria. This distinction is significant because it indicates fundamental differences in their biochemistry and survival strategies. The other options listed (A. Mode of nutrition, B. Cell shape, C. Mode of reproduction) may show variability within each domain but are not as distinctive between Archaebacteria and Eubacteria as the differences in cell membrane structure.